Clean Genome ® E. coli MDS™ 42 Glycerol Stock
类别:细胞株 货号:G-0742
人气:39 品牌:Scarab Genomics
价格:¥4,500 规格:0.4 ml
关键字: 产地:美国
种属: - 检测范围: -
表达系统(蛋白): - 抗体来源种属: -


Using synthetic biology methods, the Escherichia coli K-12 genome was reduced by making a series of planned, precise deletions. The multiple-deletion series (MDS™) strains (1), with genome reduction of up to 15%, were designed by identifying non-essential genes and sequences for elimination, including recombinogenic or mobile DNA and cryptic virulence genes, while preserving robust growth and protein production. Genome reduction also led to unanticipated beneficial properties, including high electroporation efficiency and accurate propagation of recombinant genes and plasmids that are unstable in other strains. Subsequent deletions and introduction of useful alleles produce strains suitable for many molecular biology applications.

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